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powering
next generation precision medicines
Unlock gene expression from plasma and further decode tumor and immune biology.
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ABOUT US
We are building on a simple idea–if we can see how disease behaves in real time, we can change how medicines are developed and used. We’ve built a platform that makes this possible at scale from a simple blood draw.
our SCIENCE
Our first-in-class liquid biopsy platform profiles circulating chromatin and the DNA methylome from just 1mL of plasma. This genome-wide, feature-rich space of ~20K gene promoters, ~1M gene enhancers, and ~50K CpG islands gives us resolution into the dynamic activation of individual genes and pathways.
Our technology reveals how disease behaves at the transcriptional level in real time from blood, extracting a new layer of information from cell-free DNA, a stable, well-established analyte. This allows us to see which pathways are active, which targets are expressed, and how cell states shift over time, revealing the biology behind response and resistance. Our measurements are quantitative and show strong concordance to tissue-based biomarkers, enabling consistent profiling across patients and timepoints. By capturing and decoding these signals across the genome, we reconstruct a quantitative view of disease biology from blood.
It starts in the clinic with a simple blood draw
We profile transcriptional biology using sophisticated molecular techniques
And apply proprietary machine learning approaches
To give you interpretable and actionable readouts
Expanding the universe of precision medicine
PARTNER WITH US
We work alongside drug developers to measure disease biology directly from blood—revealing mechanisms of response and resistance, informing patient selection, and guiding combination and sequencing strategies. Our platform is delivered through two products:
Precede Bio Insight™ delivers genome-wide, quantitative profiling that is consistent across patients and timepoints, enabling true longitudinal tracking of disease biology.
Precede Bio Dx™ brings this into clinical trials, enabling non-invasive patient selection based on target expression, pathway activity, and cell states
our Team
Our team brings together expertise in genomics, epigenomics, computational biology, AI, and in the development of new medicines. Together, we are building a new foundation for understanding disease, one that is dynamic, scalable, and accessible from blood.
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JOIN US
At Precede Biosciences, we believe hard problems are best solved by mission-driven colleagues who trust and genuinely care about one another. We also believe that every person on the team is essential to our success and that every one of us has the potential to change the fabric of the company, and the world, for the better. If this resonates, and you think you can contribute, then apply to an open position.

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Get in touch
1 Design Center Place, Suite 19-500, Boston, MA 02210
617.356.1457




















































